Conventional Pharmaceuticals are Ineffective and Unsafe for Peripheral neuropathy

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Treatment for peripheral neuropathy is always a challenge. In this article, we’ll discuss different approaches to treatment for peripheral neuropathy, all Pros and Cons.

Medicines used for the treatment of peripheral neuropathy

Pharmaceutical drugs

Besides medications utilized to treat problems associated with peripheral neuropathy, medications utilized to relieve peripheral neuropathy symptoms and signs consist of:

Painkillers.

Over-the-counter pain drugs, such as nonsteroidal anti-inflammatory medicines, can eliminate light signs and symptoms. For more-severe signs and symptoms, your physician might suggest painkillers.

Medications containing opioids, such as tramadol (Conzip, Ultram) or oxycodone (Oxycontin, Roxicodone, others), can bring about reliance and dependency, so these medicines usually are recommended only when other therapies stop working.

Anti-seizure medications.

Medicines such as gabapentin (Gralise, Neurontin, Horizant) and also pregabalin (Lyrica), developed to treat epilepsy, might soothe nerve discomfort. Adverse effects can include sleepiness and dizziness.
Topical therapies. Capsaicin cream, which contains a compound located in hot peppers, can trigger moderate renovations in outer signs and symptoms. You may have skin burning and also irritation where you use the lotion, yet this usually minimizes in time. Some individuals, however, can’t endure it.

Lidocaine patches are another treatment you relate to your skin that could provide discomfort relief. Side effects can consist of drowsiness, wooziness as well as tingling at the website of the spot.

Antidepressants.

Specific tricyclic antidepressants, such as amitriptyline, doxepin (Silenor, Zonalon), and nortriptyline (Pamelor), have actually been found to assist eliminate discomfort by disrupting chemical procedures in your mind and spinal cord that create you to really feel pain.

The serotonin and also norepinephrine reuptake prevention duloxetine (Cymbalta) and the extended-release antidepressant venlafaxine (Effexor XR) likewise may ease the discomfort of peripheral neuropathy caused by diabetes mellitus.

Side effects of antidepressants may consist of dry mouth, nausea or vomiting, drowsiness, dizziness, reduced appetite, and irregularity.

Therapies used for the treatment of peripheral neuropathy

Different therapies and also procedures could assist ease the symptoms and signs of outer neuropathy.

Transcutaneous electric nerve stimulation (10S).

Electrodes positioned on the skin supply a mild electrical present at differing frequencies. TENS should be obtained 30 minutes daily for concerning a month.

Plasma exchange and also intravenous immune globulin.

These treatments, which help subdue body immune system tasks, could benefit people with certain inflammatory problems. Plasma exchange entails removing your blood, after that removing antibody and various other healthy proteins from the blood as well as returning the blood to your body. In immune globulin therapy, you obtain high levels of proteins that work as antibodies (immunoglobulins).

The physical treatment used for the treatment of peripheral neuropathy

If you have muscular tissue weakness, physical therapy can assist enhance your motions. You might additionally need hand or foot dental braces, a walking cane, a walker, or a wheelchair.
Surgery. If you have neuropathies brought on by stress on nerves, such as pressure from tumors, you may require surgical treatment to reduce the stress

Effectiveness of pharmaceutical drugs for treatment for peripheral neuropathy

A current research study discovered that the four most commonly prescribed medicines for peripheral neuropathy aided extremely couple of individuals and had high discontinuation prices due to unfavorable negative effects. The research, released in JAMA Neurology in August, randomized 402 people with peripheral neuropathy of unidentified reason (cryptogenic sensory polyneuropathy) into four treatment groups and followed them for 12 weeks. The medications researched included nortriptyline (Aventyl), a tricyclic antidepressant; duloxetine (Cymbalta), serotonin-norepinephrine reuptake prevention (SNRI) antidepressant; pregabalin (Lyrica), an anti-seizure drug; as well as mexiletine (Mexitil), a medicine utilized to deal with irregular heartbeats that are frequently utilized off-label for peripheral neuropathy.
Efficiency was defined as minimizing discomfort by 50% or more. The best-performing medication was nortriptyline, which met the performance criteria for only 25% of patients. Efficiency and discontinuation prices for the 4 drugs were as complies with:

Drug                                            Effectiveness Rate                         Dropout Rate

Nortriptyline                                         25.4%                                             38.1%

Duloxetine                                            23.0%                                             37.3%

Pregabalin                                            15.1%                                            42.5%

Mexiletine                                             20.3%                                             58.0%

The researchers concluded that “while there were no clearly superior drugs, nortriptyline and duloxetine outperformed pregabalin and mexiletine when pain reduction and undesirable side effects were combined into a single endpoint”.

Conventional Medicine Has Little to Offer for the treatment for peripheral neuropathy

The goals of conventional treatment are to manage the condition causing peripheral neuropathy and relieve symptoms. If laboratory tests do not indicate any underlying condition, your doctor might recommend a watchful wait to see if your peripheral neuropathy improves. These dismal results are the best that conventional medicine has to offer neuropathic patients. When the pharmaceutical toolkit runs out, traditional doctors have no answers.
Even placebos work better as a treatment for peripheral neuropathy than these drugs, while it causing no side effects.

What is peripheral neuropathy?

If there is trauma to your nerves outside of the brain and spinal cord, you can suffer from peripheral neuropathy. It can lead to pain, numbness, and weakness, which typically occur in your feet and hands. This condition can also affect other parts of your body. The peripheral nervous system is responsible for relaying information from your spinal cord and brain to your central nervous system.

This condition can be a result of exposure to toxins, inherited causes, metabolic problems, infections, and traumatic injuries. Diabetes is also one of the most common issues. Pain from peripheral neuropathy is generally described as a tingling, burning, or stabbing sensation. With effective treatment, symptoms can show drastic improvement.

For a holistic approach, natural treatment for neuropathy can be very effective. There are various natural treatments that can mitigate the symptoms.

Peripheral neuropathy has lots of prospective causes. Besides a physical examination, which may consist of blood examinations, diagnosis generally needs:

How is Peripheral neuropathy diagnosed?

A full medical history. Your doctor will certainly examine your medical history, including your symptoms, your way of living, exposure to contaminants, alcohol consumption routines, and also a family history of nervous (neurological) illness.
Neurological exam. Your doctor could examine your tendon reflexes, your muscular tissue toughness and also tone, your capacity to feel certain sensations, and also your stance and also control.
Tests
Your medical professional might order examinations, consisting of:

Blood work.

These can detect vitamin deficiencies, diabetes mellitus, uncommon immune function, and other indications of conditions that can cause outer neuropathy.

Imaging examinations.

CT or MRI scans can try to find herniated disks, tumors, or various other problems.

Nerve feature examinations.

Electromyography (EMG) documents electrical activity in your muscles to spot nerve damages. A thin needle (electrode) is put right into the muscular tissue to measure electrical activity as you contract the muscular tissue.

At the same time as an electromyogram, your doctor or an EMG technician usually does a nerve conduction study. Level electrodes are placed on the skin as well as a low electric current stimulates the nerves. Your medical professional will tape-record your nerves’ feedbacks to the electric current.

Various other nerve feature examinations.

These may include a free reflex screen that videotapes exactly how the free nerve fibers work, a sweat test that gauges your body’s capacity to sweat, as well as sensory examinations that tape-record how you feel touch, resonance, cooling, and warmth.
Nerve biopsy. This involves removing a small portion of a nerve, typically a sensory nerve, to try to find irregularities.

Skin biopsy.

Your doctor removes a small portion of skin to search for a decrease in nerve endings.

Causes of peripheral neuropathy

There is no single factor, and various conditions lead to peripheral neuropathy such as

  • Diabetes: It’s one of the most common causes of neuropathy. Almost half of the diabetes patients develop some sort of neuropathy. Natural remedies offer a holistic and gentle treatment for neuropathy in diabetes patients.
  • Autoimmune Diseases: These include vasculitis, chronic inflammatory demyelinating polyneuropathy, Guillain-Barre syndrome, rheumatoid arthritis, lupus, and Sjogren’s syndrome.
  • Infections: Viral or bacterial infections like HIV, diphtheria, leprosy, hepatitis B and C, Epstein-Barr virus, shingles, and Lyme disease.
  • Bone marrow disorders: myeloma, amyloidosis, lymphoma, and monoclonal gammopathies can also lead to this condition.
  • Tumors: cancerous and non-cancerous tumors can develop on the nerves and press nerves.
  • Inherited disorders: Conditions like Charcot-Marie-Tooth are hereditary forms of neuropathy.

Causes of Peripheral Neuropathy

  1. Diabetes – tops the list of causes of peripheral neuropathy

Diabetes is one of the most common causes of peripheral neuropathy is Diabetes can trigger chronic peripheral neuropathy. High blood sugar level levels can harm nerves, primarily in the feet. This is why peripheral neuropathy regularly happens in people whose blood glucose is not controlled than those who preserve reduced blood glucose degrees. Diabetic neuropathy as a result of unchecked blood sugar degrees can create irreparable damages to the nerves. When diabetic issues is under control, the amount of sugar in the blood continues to be at a safe degree, thus decreasing the danger of prospective nerve damages.

  1. B12 Vitamin Deficiency – one of the common causes of peripheral neuropathy

A vitamin B12 shortage can damage the entire body, leading to symptoms such as lightheadedness, general weakness or absence of energy, shortness of breath, muscle pains, and heart palpitations. It takes second place on the list of the most common causes of peripheral neuropathy. A lack of vitamin B12 can additionally cause peripheral neuropathy. The protective layer around the nerves, the myelin sheath, swiftly ends up being harmed when there is insufficient B12. Without this layer of protection, the nerves might stop operating correctly, leading to peripheral neuropathy.
3. Radiation treatment
If we are talking about causes of peripheral neuropathy radiation therapy takes a special place. Professionals break down neuropathy into two classifications: mononeuropathy and polyneuropathy. The previous affects only one nerve, while the latter affects numerous nerves at the same time. The results of chemotherapy can harm lots of nerves throughout the body; radiation treatment can have a similar effect. Fortunately, is that numerous clients recoup from a few of the damages related to chemotherapy-induced outer neuropathy after the treatments are full.

  1. Toxic substances such as heavy metals may become a cause of peripheral neuropathy.

In some cases, contaminants or poisonous substances, consisting of pesticides and chemicals, can top the list of causes of peripheral neuropathy, especially when a person is subjected to larger top qualities of these chemicals, via a ranch job, for example. Direct exposure to chemicals in the work environment, specifically over a long period, can trigger nerve damages. Common perpetrators consist of mercury, lead, thallium, and arsenic. Recreational medications including specific chemicals can additionally create neuropathy.

5. Cancer – another common cause of peripheral neuropathy.

Some sorts of cancer cells can lead to peripheral neuropathy, specifically cancers that impact the nervous system. Lumps that expand in or near the brain or spine, especially, can bring about nerve damage. However, any cancer that causes the growth of tumors can bring about neuropathy if, as the growth grows, it continues the nerves.

6. Injuries – mechanical cause of peripheral neuropathy.

After diabetic issues, an injury is the next most common root cause of peripheral neuropathy. When injury harms a muscle or cells, the surrounding tissues start to swell, which can damage the nerves. Similarly, when a bone breaks, the broken sides or bone fragments can quickly harm the nerves. This is why it is vital to see a doctor asap when complying with an injury. Walking around on a neglected busted ankle joint will raise the danger of peripheral neuropathy.

7. Infection – bacterial cause of peripheral neuropathy.

Some infections can straight cause peripheral neuropathy. Those that produce substantial inflammatory feedback are the main cause of inflammatory neuropathy. In this situation, as the immune system strives to recover the body, it might erroneously assault the nerves and the nervous system, too. Problematic infections include Lyme condition, human immunodeficiency virus (HIV), as well as tiles. Symptoms of peripheral neuropathy normally improve once the infection is under control or has been removed. Nevertheless, in more severe cases, some signs of peripheral neuropathy might continue long-term.

8. Kidney Disease

One more feasible source of causes of peripheral neuropathy is kidney condition, which establishes when the kidneys are incapable to execute their important task of eliminating waste from the body. Consequently, waste and excess liquids build up and, when the kidneys stop working, nerves damaged by an imbalance of chemicals, and the salts in the body can cause peripheral neuropathy.

9. Inflammatory Diseases

Inflammatory illnesses such as sarcoidosis as well as gastric condition can lead to peripheral neuropathy. Lots of physicians consider neuropathy a very early indication of Celiac condition. This autoimmune inflammatory condition triggers damage to the little projections that line the intestines, called villi. When an individual with this condition remains to eat foods having gluten, the villi start to shorten as well as squash, triggering many illnesses, including neuropathy.

10. Idiopathic

Idiopathic outer neuropathy is a sort of neuropathy for which the cause is unknown. In today’s age of scientific screening and developments, this is rare. People with this type of neuropathy can go through the exact same treatments like those for whom a reason has actually been identified, however more trial and error might be essential to find the most useful treatment.

Most Typical Symptoms of peripheral neuropathy

If you have actually experienced tingling, pins, and needles, or acute pains in your feet or in your hands, it is most likely that you have actually experienced peripheral neuropathyPeripheral neuropathy does not describe a particular condition, however instead from nerve damages that might be caused by a number of different points.

The most common peripheral neuropathy symptoms are:

  • Paralysis if motor nerves are affected
  • A sensation of wearing socks and gloves even when you’re not
  • Muscle weakness
  • Lack of co-ordination
  • Pain while performing activities that normally shouldn’t cause pain
  • Extreme sensitivity to touch
  • Burning, throbbing, jabbing, or sharp pain
  • The gradual development of tingling, prickling, or numbness in your hands or feet can spread to your arms and legs

Symptoms of peripheral neuropathy

There are several things that can cause damage to the nerves and also as a result of this, the symptoms of peripheral neuropathy will certainly vary from one person to another. If peripheral neuropathy is not treated it can intensify to a factor where it hinders the lifestyle of an individual. The good news is that there are a number of lifestyle adjustments that can be made in order to reverse or decrease the progression and also signs and symptoms triggered by nerve damages.

In order to discover peripheral neuropathy early, it is important to understand several of one of the most usual signs and symptoms of peripheral neuropathy. Right here are 8 of the most typical peripheral neuropathy signs.

1. Discomfort – common symptoms of peripheral neuropathy.

The discomfort that is experienced from peripheral neuropathy is generally really specific. This discomfort is frequently called a pain, burning, or stabbing feeling. No matter how it really feels, this discomfort is tough to overlook. Discomfort from peripheral neuropathy occurs since the fibers of the nerves have been damaged. These damaged fibers will after that send out signals that are jumbled or wrong to the different pain facilities of the body.

The pain happens in various locations of the body based on the kind of neuropathy that has actually created. For people who have diabetes mellitus, neuropathy will certainly most often show up in the feet first. Neuropathy that is caused by an injury or some type of trauma will certainly happen at the place the injury happened. Discomfort in the wrist and also arm triggered by repetitive strain injury is one example. If you experience this type of discomfort it is necessary to discuss it with your doctor to identify the underlying reason.

2. Feeling numb and Tingling – #1 on the list of symptoms of peripheral neuropathy.

Numbness is one of the most common symptoms of peripheral neuropathy. When the sensory nerves have been damaged as a result of peripheral neuropathy, prickling or a sensation of pins and needles are rather common. Feeling numb will certainly usually happen in the feet initially and after that work its means up via the rest of the body. As an example, an individual might experience tingling in their feet initially, and afterward, this tingling will certainly spread out right into the legs. Pins and needles might additionally begin in the hands and afterward move into the arms.

Lots of people do not believe way too much about pins and needles as they will frequently disappear. However, it can be an indication of severe trouble for a number of reasons. You are more likely to become damaged due to the fact that you cannot feel a part of your body. As an example, if your foot becomes numb as well as you step on something sharp, you may lose quite a bit of blood before you also observe. Diabetics typically run the risk of shedding afoot because of this sort of injury that they simply do not feel.

Symptoms of peripheral neuropathy

3. Foot Issues

A person who has peripheral neuropathy might experience major concerns with their feet. Any kind of foot concerns an individual is experiencing is typically an indicator of diabetic peripheral neuropathy. When pins and needles in the feet happen it substances a number of the various other issues that a diabetic person is dealing with as it boosts the danger of creating a serious injury or an infection. On top of that, nerve damage that is related to neuropathy may likewise trigger the size and shape of an individual’s foot to transform.

4. Digestive system Concerns

There are some sorts of neuropathy that have an effect on the sensory nerves. Various other sorts of neuropathy can affect the autonomic nerves. These are the nerves that manage the organs. There are some nerves that control the digestion of body organs. When these nerves come to be harmed it can cause a person to experience gastrointestinal concerns. One symptom of this sort of nerve damage is constipation. In many cases, an individual might experience the contrary and have severe diarrhea if these nerves are harmed.

Symptoms of neuropathy

It is likewise quite typical for individuals to alternating these problems, experiencing looseness of the bowels complied with by bowel irregularity. Neuropathy might also cause concerns with the nerves that regulate a person’s bladder. This might bring about signs and symptoms like incontinence or a boost in urinary tract infections. Belly problems may likewise be brought on by peripheral neuropathy. Gastroparesis, which is when the belly is slow-moving to vacant is a common sign that may accompany neuropathy.

5. Law Body Temperature

When a person has damages to their nerves, they may locate that they have a problem regulating the temperature level of their body. A person may have difficulty sweating, even when it is warm. They may additionally have the opposite problem where they simply sweat frantically. For some people, a high external temperature level can be rather excruciating. The factor for this is because their bodies can no longer efficiently locate a method to cool off when it is warm.

Some people may experience chilly cool and also seem like they are never ever going to be cozy once more. Every one of these is a sign that an individual has some sort of nerve damages. In order to figure out the underlying cause it is essential to discuss your signs and symptoms with your physician. When the root cause of this symptom is known, proper treatment can be provided in order to make you far comfier in the long term.

6. Muscle Weakness as well as Convulsion

Neuropathy can affect the nerves that are accountable for regulating the motions of the muscle mass. One of the usual symptoms of this kind of peripheral neuropathy is a twitch in the muscle. Some individuals experience constraining as a sign when this takes place. Some individuals who have genetic neuropathy are more likely to additionally create the signs and symptoms of weak points in the muscular tissues.

The muscles in the body could simply atrophy or waste away. Relocating or perhaps simply standing can become quite difficult. In a severe instance of nerve damage, an individual that has established motor neuropathy can experience paralysis in particular muscular tissue areas.

An additional type of peripheral neuropathy associated with diabetic issues can result in atrophy or muscular tissue weakness. This type is called radiocomplexes and also generally takes place in the buttocks and also upper legs. This most often will certainly take place on one side of the body or the various other. Standing up after sitting for a long period can be a battle.

7. Fainting

The free nerves control the blood pressure as well as your heart price. When the nerves come to be damaged it is common for a person to experience a sudden decrease in their blood pressure. This will commonly take place when a person rises from lying down or simply from standing up from sitting.

This quick drop in the blood pressure might trigger a person to really feel woozy and sometimes, they might really collapse. It is common for somebody to get up too quickly as well as really feel a little lightheaded. This is something virtually everyone has actually experienced at some point or an additional.

Nonetheless, if this takes place quite often and a person does really pale after merely standing up from a sitting or a lying-down setting, there is a good chance that it is brought on by some sort of nerve damages. If you are experiencing these signs and symptoms it is necessary to see your physician immediately to establish the reason.

8. Hypoglycemia Unawareness

Diabetic neuropathy is one of the most usual neuropathy types. Consequently, it is necessary to take into consideration one of the signs that only influences diabetics. Hypoglycemia unawareness happens when blood sugar level degrees are up to unsafe levels as well as the body does not experience symptoms that are typical.

In typical circumstances, when the blood glucose levels drop instantly the body will release epinephrine. This will make the person experience heart palpitations or sweat profusely. These prevail indications of having low blood sugar levels. However, when a person is suffering from hypoglycemia unawareness, the epinephrine does not get launched when the degrees of blood sugar fall.

When this occurs and also an individual does refrain from anything to increase the levels of blood glucose, loss of consciousness or complication might occur. These signs and symptoms usually occur with the epinephrine action nerves have actually been damaged. It is most typical in individuals who have kind 1 diabetes mellitus however can be experienced by those with type 2 diabetes issues as well.

9. Deferred Pain

Deferred discomfort suggests that the discomfort you are really feeling isn’t essential at the site of the damage or level of sensitivity. Simply put, it implies that you may have a problem with your back, yet this is after that actually really felt in your legs or your hip.

There are a lot of reasons that you may get delayed discomfort. One is that you may have a muscle inequality. For instance, if you have a very limited muscle in your back or part of your legs, after that this can create tension on the joints or on another part of your body. That then could create you to occupy a corrective stance, to make sure that you are strolling and also moving with bad type. The pain may be really felt somewhere entirely different, as a result! As well as interestingly, research studies taking a look at the role of fascia in the body show this communication may be a lot more intricate than we in the beginning idea.

Yet what’s additionally feasible is that this suggests neuropathy. Bear in mind, you have a big network of nerves running throughout your body, some of which are very long. That means that damaging one nerve may cause shockwaves of pain that travel throughout your body as well as you might for that reason really feel the discomfort someplace completely various.

10. Loss of Vision

Neuropathy is not a single problem but is rather a symptom that can occur for a myriad of factors. Also, neuropathy can describe damage to nerves situated throughout your body, as well as with a vast array of various crucial functions. This can make it difficult to detect the original issue, and even to recognize whether the problem is without a doubt best-called neuropathy.

Loss of vision is an instance of this. You can suffer a loss of vision as a result of damages to the nerves in the eye. These relay signals in between your mind and also your retina– as well as actually, some individuals even describe the eye as the only exterior part of the mind’.

There are many factors that can experience damage to the nerves in the eye. One of the most usual though is diabetes. Diabetes mellitus is caused by a boost in sugar in the blood, which subsequently results from modifications in insulin production. Because sugar is in fact very harmful in huge amounts, this can then in fact be enough to cause substantial damages to the nerves– which results in tingling in the hands and also loss of vision.

Some approaches to a natural treatment for peripheral neuropathy

Natural treatment for neuropathy is effective and safe. In the majority of cases neuropathy is the result of diabetes and for this category of patients, natural treatment is even more important considering the number of pharmaceutical drugs they are receiving on a regular basis.

There are various Natural remedies for neuropathy that can offer relief from symptoms without the side effects associated with conventional treatments. The effectiveness of natural remedies for neuropathy had been proven by scientific studies.

Neuropathy has various symptoms, and can it can seriously affect your life. In the United States alone, about 20 million people are estimated to be suffering from some sort of peripheral neuropathy. However, keep in mind that these numbers may be way higher as many people with this condition are not tested. If the root cause of the neuropathy is ascertained, it’s possible to find long term solution. Earlier treatments lead to better outcomes.

If you’re suffering from this condition, you might consider a natural treatment for neuropathy. They are effective, affordable, and can get to the root of your condition. Further, they have no known side effects.

Natural treatment for peripheral neuropathy usually is safe and affordable. In many cases, natural treatment for peripheral neuropathy is much more effective than the conventional use of pharmaceutical drugs.

  • Cannabinoids Marijuana and CBD – effective pain relief natural treatment for peripheral neuropathy

The scientific literature demonstrates some efficacy of medical marijuana/cannabis in the treatment of chronic neuropathic pain. Clinical studies of different routes of administration (sublingual, oral, smoked, and vaporized) have shown an analgesic benefit in the treatment of this costly and disabling condition, and some guidelines for the treatment of neuropathic pain recommend taking consider cannabinoids as a second or third-line agent.
Because medical marijuana expenses are not covered by health plans and are out of your own pocket, knowing the cost-effectiveness of medical marijuana can influence patients’ decisions about its use. According to newly issued research, inhaled cannabis appears to be reasonably priced when used as a second or third-line curing approach in persistent neuropathic pain.

  • Acupuncture – Traditional Chinese natural treatment for peripheral neuropathy

We recently looked at the evidence for acupuncture in the treatment of peripheral neuropathy. We systematically reviewed 46 clinical trials and included 13 qualifying randomized controlled trials of acupuncture versus sham acupuncture or standard medical therapy and concluded that acupuncture is effective in treating diabetic neuropathy, Bell’s palsy, tunnel syndrome. carpal and is most likely effective for the treatment of HIV-related neuropathy.

Acupuncture for peripheral neuropathy

Acupuncture for neuropathy has been well documented for its effectiveness and safety. In fact, for chronic conditions, acupuncture can provide outstanding results. Acupuncture for neuropathy utilizes thin needles, which are inserted into specific points to stimulate your nervous system. This releases your body’s natural painkillers known as endorphins in the brain, spine, and muscles. This method changes the way your body reacts to pain. It also stimulates blood flow to heal nerve damage.

Acupuncture has no known side effects making it viable for even diabetic patients. If you want a powerful natural treatment for diabetic neuropathy in feet or any other parts of your body, acupuncture can be an effective treatment. A study conducted in 2007 showed that Acupuncture for neuropathy is very effective in reducing neuropathy symptoms.

In the Neurology Wellness Clinic at OHSU, we routinely treat patients with peripheral neuropathy and some of our best results are with idiopathic neuropathy (the meaning of unknown cause). A typical course of treatment consists of weekly electroacupuncture sessions for 6-8, sometimes 10 weeks, followed by gradual spacing every other week, every three weeks, once a month, and possibly a maintenance treatment once every 2-3. months.

Acetyl-L-carnitine is a chemical compound that is naturally produced in the kidneys and liver. Acetyl-L-carnitine helps reduce oxidative stress. It is believed to be involved in the function and regeneration of nerve cells.
In some clinical trials, people who had diabetic neuropathy had reduced pain, improvements in other sensory problems, and improvements in nerve function tests. Some of these studies have also suggested that the effect of treatment is greatest when started early in the course of the disease. Further studies are needed.
ALC dietary supplements available over the counter and commonly considered safe when consuming as directed. Side effects can include nausea, vomiting, or agitation.
Do not use acetyl-L-carnitine if you use warfarin (Coumadin, Jantoven), a blood-thinning drug because the combination increases the effect of warfarin and potentially the risk of bleeding. For people who have hypothyroidism or a history of seizures, acetyl-L-carnitine can make these conditions worse.

Curcumin – the main ingredient of Turmeric is a culinary herb known for its anti-inflammatory, antioxidant, and analgesic properties. It can help to relieve numbness and tingling in the hands and feet. It is available as a supplement, or you can take 1 teaspoon of turmeric powder with 1/4 teaspoon of ground pepper three times a day.
Similarly, you can consume fresh or powdered turmeric to prepare tea. You can add it to foods like curry, egg salads, and yogurt smoothies.
2014 animal study found that curcumin reduced chemotherapy-induced neuropathy in mice that took it for 14 days. It had a positive effect on pain, inflammation, and functional loss. Levels of antioxidants and calcium have improved significantly. Larger studies in humans are needed to expand these findings.
2013 research indicates that curcumin is useful when taken during the early stages of neuropathy. This can prevent the development of chronic neuropathic pain.

Lasers provide light in a highly concentrated way specified by a high degree of spatial and also temporal comprehensibility. Lasers involve high-intensity photo-bio excitement of a tool, which can be a gas, liquid, crystal, color, or semiconductor, leading to the exhaust of photons.

Low level laser treatment for peripheral neuropathy

The two major categories of laser treatment are class IV as well as class III, which are differentiated according to result power. Low-level laser treatment is a course III laser as well as requires only a discrete amount of outcome intensity or energy (5-500 mW) to yield a medical action. Power discloses a biphasic dose-response in which higher intensities hinder instead of facilitating mobile and also scientific response.58 Low-level lasers run within the concepts of bioorganic photochemistry, a technique of scientific research that discovers the interaction in between photons as well as biochemical pathways in cells.

The scientific energy of low-level laser treatment is originated from the capability to regulate mobile metabolism as well as influence a diverse variety of intracellular biochemical waterfalls that straight impact cellular habits and also feature.

The organic impact of coherent laser irradiation on cells is labeled photobiomodulation. All light is radiation power that is gauged in discrete devices called photons, as well as its effect on cellular components, is moderated by organic photo-acceptor particles that are located in a range of cellular components throughout the human body.

Two mobile parts specifically that have actually been identified are cytochrome c oxidase, which belongs to the electron transportation chain of mitochondria, and also porphyrins, which are discovered in the eukaryotic cell membrane.

Cytochrome c oxidase is a multi-component membrane protein, which has a binuclear copper center (CuA) and a heme binuclear center (a3-CuB). Cytochrome c oxidase promotes the transfer of electrons from cytochrome c to oxygen, driving oxidative phosphorylation.59,60 Researchers think low-level laser stimulation of cytochrome c oxidase increases the transfer price of electrons and makes more electrons available for the decrease of dioxygen.61-69 Useful modifications in the incurable enzyme raise the membrane layer possibility and also proton slope, altering mitochondrial optical residential properties and boosting the price of ADP/ATP exchange.70,71.

The combination of upregulation of ATP, as well as upregulation of responsive oxygen varieties, directly influence additional reactions that regulate gene expression, protein as well as development element synthesis, cell spreading, and lots of other mobile homes. Upregulation of ATP is coupled to the manufacturing of responsive oxygen species, which can impact the intracellular redox state. Sensitization of key afferent nociceptors is worsened by TNF-α and also various other pro-inflammatory cytokines.72 Synthesis of pro-inflammatory cytokines such as TNF-α takes place by means of the inducible enzyme COX-2, which militarizes the formation of prostaglandin H2 from arachidonic acid.68 Both prostaglandin E2 (PGE2) and also prostacyclin promote pain by promoting the pain-producing device of bradykinin as well as other autacoids.71-73.

Several courses of non-opioid anesthetics act as certain inhibitors of COX-2 and prevent eicosanoid formation.74-78 In vitro and also in vivo studies have revealed that laser treatment decreases PGE2, interleukin-1α, and TNF-α by preventing COX-2.55 -57 One theory is that laser treatment influences the intracellular redox state by modulating the transcription variable nuclear factor kappa B, which goes through phosphorylation and also ubiquitination, and advertises proteolytic deterioration of IKB-a under oxidative anxiety. A change in the intracellular redox state may affect the cascade in charge of controlling COX-2 expression, thus subduing the synthesis of pro-inflammatory cytokines.

Researchers have actually shown that low-level laser treatment upregulates VEGF, which promotes neovascularization.54 Improved microcirculation may contribute to the stabilizing of cell metabolism by increasing cellular nutrient and oxygen concentrations.

PEMF therapy is a safe and non-invasive tool for improving health. It stimulates and reproduces the natural electromagnetic frequencies of the Earth and essentially functions as a charger for the body’s electric battery.
The most important benefits are increased energy and circulation; reduction of muscle spasms; improved sleep; improved healing of bone fractures; and reduction of pain and inflammation. According to Bryant A. Meyers, “the body self-heals, self-regulates, and self-regenerates.” PEMF therapy basically helps provide the energy needed to do this.

Scrambler Therapy (marketed as Calmare ™ therapy in the United States) is a new type of pain relief that uses a rapidly evolving electrical pulse to send a “painless” signal along the same pain fibers that send the “pain” stimulus. We got interested in Scrambler Therapy because we thought it COULD help CIPN patients and Scrambler Therapy appeared to be non-toxic. It had been cleared for safety by the FDA in 2009.

This video from March 2020 shows HPT technology in a new wearable patch, just like the HPT technology woven into these socks. Showing the brain mapping effect.
As stated above and in this clinical study, the HPT impregnated socks developed by VoxxLife provide significant relief from nerve pain. (All VoxxLife socks come with built-in HPT technology).

  • Essential Oils – home-based natural treatment for peripheral neuropathy

If you looking for the safest and affordable, natural treatment for neuropathy, essential oils for neuropathy can be a wonderful option. Some essential oils for neuropathy like Roman lavender and chamomile can effectively increase your body’s circulation. They also possess anti-inflammatory and anti-bacterial properties that can quicken the recovery process. To use essential oils as a treatment for neuropathy in feet and legs, simply apply the essential oils in the affected area. 

They possess no known side effects, and in conjunction with other natural remedies, the results can be outstanding. However, you’ll need some time before you see results.

2014 study compared the effectiveness of Swedish massage using aromatic ginger oil to traditional Thai massage in 140 older adults with chronic low back pain.
Although both treatments improved symptoms, Swedish massage with aromatic ginger oil was more effective than Thai massage in reducing pain and disability.
Ginger oil contains an ingredient called Zingibain, which has prevailing anti-inflammatory properties. Thus, Zingibain may help reduce neuropathic pain resulting from inflammatory conditions.

Borneol, a compound of chamomile and lavender essential oils, may help reduce pain and inflammation associated with neuropathy.
2015 study found borneol reduced pain sensitivity in mice with neuropathic pain. However, further research will be required to confirm the effect in humans.

St. John’s wort, or Hypericum perforatum, is a traditional remedy for depression and anxiety. People also use the extracts to treat burns, inflammation, and nerve pain.
According to a 2017 report, a person with trigeminal neuralgia – a type of nerve pain that affects the face – found that a homeopathic remedy for St. John’s wort helped relieve symptoms.
The report’s authors concluded that St. John’s wort “may be a promising therapeutic option” for treating this pain, but further research is needed.

Vitamins for Neuropathy – Another essential Part of Natural Treatment for Neuropathy

In some cases, peripheral neuropathy is related to vitamin deficiencies. Vitamin B6 and B12 are critical for your nerve health. If you’re suffering from Vitamin B deficiency, it can lead to major nerve damage. You can receive Vitamin B from your meals, but you can also consult your doctor for supplements.

Vitamins B can also offer remedies for nerve pain. Deficiency in Vitamin D can lead to neuropathy. You can take supplements to reduce the symptoms.

Treatment of peripheral neuropathy with homeopathic medicines

Homeopathy is one of the most popular systems of holistic medicine. The selection of remedies is based on the philosophy of individualization and similarity of manifestation using a holistic approach.

This is the only way to get back to a full state of health by removing all the signs and symptoms from which the patient is suffering. The goal of homeopathy is not only to treat the symptoms of peripheral neuropathy but also to address its underlying cause and individual sensitivity. Regarding therapeutic medication, several remedies are available for the treatment of peripheral neuropathy which can be chosen depending on the cause, sensations, and modalities of the complaints. For tailored individualized homeopathic prescriptions, an individual should consult a skilled and well-trained homeopathic practitioner in person. There are the following remedies that are helpful in treating peripheral neuropathy:

  • Pulsatilla,
  • Graphites,
  • Causticum,
  • Phosphoric Acid,
  • Gelsemium,
  • Baryta Carbonica,
  • Picric Acid,
  • Sepia, Silicea,
  • Agaricus,
  • Mercurius,
  • Sulphur,
  • Lachesis,
  • Cuprum Metallicum,
  • Rhus Toxicodendron and many other medicines.

Conclusion

Victor Tsan, MD, the medical director of the Philadelphia Holistic Clinic is an integrative medicine practitioner with 40+ years of academic and clinical experience in OBGYN and internal medicine. Find his professional profile HERE Dr. Tsan is also available for online evaluations during the pandemic.

f you suffer from any form of neuropathy, you must seek treatment as soon as possible to prevent long term consequences. The natural remedies for neuropathy mentioned above are not only safe but have a proven record of effectiveness. You might have to experiment with a few options before finding what works better for you. In many cases where allopathic treatments fail to produce results, natural treatment for neuropathy appears to be beneficial. Besides, they have no known side effects and can be used in various demographic areas. 

At the Philadelphia Holistic Clinic, Dr. Tsan gathered the best in class certified holistic providers. All forms of natural treatment for neuropathy are available under one roof at the clinic.

If you need an appointment for a holistic evaluation, contact Philadelphia Holistic Clinic at (267) 284-3085 or use our online scheduling application

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